Endocrine Abstracts

Purpose: To evaluate safety and efficacy of percutaneous radiofrequency ablation therapy for unilateral aldosterone producing adrenal adenoma in normalising aldosterone secretion.Patients: Eight cases of aldosterone producing adrenal adenoma with following conditions: i) CT detectable adenoma without any risky organs on a puncture route. ii) Intervening adipose tissue between target adenoma and adjacent risky organs (pancreas or intestine). iii) Unilater...

The pathophysiology of aldosterone-producing adenomas (APA), especially those manifesting clinically overt hyperaldosteronism despite their small size, remains unknown. Therefore, we examined the correlation between tumor size and the status of intratumoral steroidogenic enzymes involved in aldosterone biosynthesis using immunohistochemistry. Forty patients with surgically proven APAs following adrenal venous sampling were retrospectively studied. The tumor area at the maximum...